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New ubiquitin chemistry regulates life processes

December 2016. Phosphoribosylation of ubiquitin promotes serine ubiquitination and impairs conventional ubiquitination


DFG award for international marketing concept

December 2016. International marketing concept of UBAUT networks receives DFG award


SFB 1080 funding extended

November 2016. €12 million for research in the Rhine-Main area on molecular and cellular mechanisms of neural homeostasis


Structure of RNA polymerase I transcribing ribosomal DNA genes

November 2016. Structure with and without nucleic acids solved at 3.8 Å resolution by cryo-electron microscopy


Resolving the end-point of protein production

November 2016. Structure of ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry


Sweetening neurotransmitter receptors and other neuronal proteins

October 2016. Researchers discover a “sugar-code” for neuronal membrane proteins


Recognition of enzymes lacking bound cofactor by protein quality control

October 2016. Newly synthetized enzymes must fold correctly and associate with cofactors to reach their functional state. Frankfurt scientists led by Martin Vabulas have now demonstrated that cofactor deprivation due to vitamin...


Novel insights into the replication mechanisms of the influenza virus

October 2016. Pre-initiation and initiation conformations of virus promoter RNA probed by single-molecule FRET


Light control of complex scenarios

October 2016. Three-dimensional control of DNA hybridization by orthogonal two-color two-photon uncaging


Unveiling the ubiquitin fingerprint induced by Salmonella infection.

September 2016. Bacterial invasion impacts several critical pathways of the host cell


Antigenic peptide recognition on the human ABC transporter TAP resolved by DNP-enhanced solid-state NMR spectroscopy

September 2016. The human transporter associated with antigen processing (TAP) selects peptides for export into the endoplasmic reticulum and subsequent loading onto major histocompatibility complex class I molecules to trigger...


New structural information on growing microtubule ends

September 2016. EB1 interacts with outwardly curved and straight regions of the microtubule lattice


New role of RNA editing in vascular disease

September 2016. Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation


Structure of a complete yeast ATP synthase dimer shows molecular basis of inner mitochondrial membrane morphology

August 2016. Previously unknown subunit architecture of the dimer interface in the membrane revealed


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